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I-Topicastat inefuthe lokuthintela ukhuphiswano kwi-xanthine oxidoreductase, ngaloo ndlela inqanda ukuveliswa kwe-uric acid.Ayinayo i-inhibitory effect kwezinye i-pyrimidine purine metabolizing enzymes, kodwa ngokukhethayo inqanda umphumo we-Chemicalbook kwi-xanthine oxidoreductase.I-Topicastat inempembelelo ebalulekileyo yokuthintela kuzo zombini i-XOR ene-oxidized kunye nencitshisiwe, ngoko ke umphumo wayo wokunciphisa uric acid unamandla kwaye uqinile, ngoko le mveliso ingasetyenziselwa unyango lwe-hyperuricemia engapheliyo kwi-gout.