Flubendazole |31430-15-6
Inkcazo yeMveliso:
I-Flubenzimidazole sisinambuzane sokwenziwa sebenzimidazole esinokunqanda ukufunxwa kwe-nematode kunye nokudityaniswa kwe-intracellular microtubules.
Inokuba nobudlelwane obuqinileyo ne-tubulin (i-dimer subunit protein ye-microtubules) kwaye inqanda ii-microtubules kwi-polymerizing kwiiseli zokufunxa (okt iiseli zokufunxa kwiiseli zamathumbu e-nematodes).Inokuqinisekiswa ngokunyamalala kwe-microtubules (elungileyo) ye-cytoplasmic kunye nokuqokelela kweengqungquthela ze-secretory kwi-cytoplasm ngenxa yokudluliselwa okuvaliweyo.
Ngenxa yoko, i-membrane ye-membrane yokugquma iba yincinci, kwaye amandla okugaya kunye nokufunxa izondlo ziyancipha.Ngenxa yokuqokelelwa kwezinto ezifihliweyo (i-hydrolases kunye ne-proteolytic enzymes), iiseli zifumana i-lysis kunye nokuncipha, ekugqibeleni zikhokelela ekufeni kwe-parasite.
Isicelo:
I-Flubenzimidazole yi-wide-spectrum yokugxotha izinambuzane ezinokuthi zinyange ngokufanelekileyo ii-parasites ezinjeni, ezifana ne-gastrointestinal roundworms, hookworms, kunye ne-whipworms;Kwangaxeshanye, inokunyanga iintsholongwane ezininzi zesisu kwiihagu kunye neenkukhu, ezifana ne-Ascaris suum, i-Hyostrongylus rubidus, i-Oesophagostomum dentatum, i-Trichuris suis, i-Metastrongylus apri, njl.
I-Flubenzimidazole ayinakubulala abantu abadala kuphela kodwa namaqanda.
Iphakheji: 25 kgs / ibhegi okanye njengoko ucela.
Ugcino: Gcina kwindawo engenamoya, eyomileyo.
Umgangatho wesiGqeba: uMgangatho waMazwe ngaMazwe.
