UMelittin |20449-79-0

I-Melittin yityhefu yepeptide efumaneka kwityhefu yenyosi, ngakumbi kwityhefu yenyosi (Apis mellifera).Ngenye yezona zinto ziphambili ze-bee venom kwaye igalelo kwimiphumo evuthayo kunye nentlungu ehambelana nezinyosi.I-Melittin yipeptide encinci, i-linear equkethe i-26 amino acids.

Iimpawu eziphambili ze-melittin ziquka:

Ulwakhiwo: I-Melittin inesakhiwo se-amphipathic, oku kuthetha ukuba ineendawo zombini ze-hydrophobic (i-water-repelling) kunye ne-hydrophilic (enomtsalane wamanzi).Esi sakhiwo sivumela i-melittin ukuba idibanise kunye nokuphazamisa iimbumba zeeseli.

Indlela yokuSebenza: I-Melittin yenza iziphumo zayo ngokusebenzisana neembrane zeseli.Iyakwazi ukwenza ii-pores kwi-lipid bilayer ye-membrane zeseli, ekhokelela ekwandeni kokungena.Oku kuphazamiseka kweembrane zeeseli kunokubangela i-cell lysis kunye nokukhululwa kwemixholo yeselula.

Impendulo evuthayo: Xa inyosi ihlaba, i-melittin ifakwe esikhumbeni sexhoba kunye namanye amacandelo etyhefu.I-Melittin inegalelo kwiintlungu, ukudumba, kunye nokubomvu okuhambelana nezinyosi ngokubangela impendulo yokuvuvukala.

Iipropati ze-Antimicrobial: I-Melittin iphinda ibonise iimpawu ze-antimicrobial.Kuye kwafundwa ngokukwazi ukuphazamisa i-membrane yebhaktheriya, i-virus kunye ne-fungi, iyenza ibe yinto enomdla kwizicelo ezinokuthi zonyango, ezifana nokuphuhliswa kwee-antimicrobial agents.

Izicelo ezinokuthi zenzeke zonyango: Nangona indima yayo kwintlungu kunye nokuvuvukala okubangelwa yizinyosi, i-melittin iphandwe ngenxa yokusetyenziswa kwayo konyango.Uphando luye lwahlola iimpawu zalo ezichasayo kunye ne-anticancer, kunye namandla alo kwiinkqubo zokuhanjiswa kweziyobisi.

Umqulu:25KG/BAG okanye njengoko ucela.

Ugcino:Gcina kwindawo engenamoya, kwindawo eyomileyo.

IsigqebaUmgangatho:Umgangatho wamazwe ngamazwe.