Hydrolyzed Collagen |92113-31-0

Ingcaciso yeMveliso:

Emva kwe-enzymatic hydrolysis ye-collagen, inokuba yi-hydrolyzed collagen (i-Hydrolyzed Collagen, eyaziwa ngokuba yi-collagen peptide).

I-Collagen polypeptide iqulethe iindidi ezili-19 zee-amino acids.I-Collagen (ekwabizwa ngokuba yi-collagen) yiprotheni yesakhiwo se-extracellular matrix kwaye iyona nxalenye ephambili ye-extracellular matrix (ECM), ibalwa malunga ne-85% yezinto eziqinileyo ze-collagen fibers.

I-Collagen yiprotheni ekhoyo yonke indawo emzimbeni wezilwanyana, ngokukodwa kwi-tissue edibeneyo (ithambo, i-cartilage, isikhumba, i-tendon, ukuqina, njl.) 6%.

Kwizinto ezininzi eziphila elwandle, ezifana nesikhumba sentlanzi, isiqulatho sayo seprotheyini sifikelela kuma-80%.

Umsebenzi weHydrolyzed collagen

I-Hydrolyzed Collagen isetyenziswa kakhulu kwizinto zokuthambisa, ezinemisebenzi efana nokuchasana nokushwabana, ukwenza mhlophe, ukulungisa, ukuthambisa, ukucocwa, kunye nokuphucula ukunwebeka kolusu.

I-Hydrolyzed Collagen inokusetyenziswa kwiimveliso zokhathalelo lomzimba, ezinokuthi zisebenze iiseli, ziphucule amajoni omzimba, zichase ukuguga, zithintele ukuguga kwesikhumba, zinciphise ubunzima, zithobe umzimba, zikhulise ibele, njalo njalo.

Indlela yokuvelisa ye-Hydrolyzed Collagen

I-Hydrolyzed collagen itsalwa emathanjeni kunye nolusu lwezilwanyana eziye zahlala zodwa, kwaye iiminerali emathanjeni naselusuni zixutywe ne-acid-grade dilute acid.Ihagu okanye intlanzi) emva kokunyangwa nge-alkali okanye ngeasidi, amanzi e-osmosis aphezulu ahlambulukileyo asetyenziselwa ukukhupha iprotheni ye-collagen ye-macromolecular kubushushu obuthile, emva koko ngenkqubo ekhethekileyo ye-enzymatic hydrolysis, ikhonkco le-macromolecular liyasikwa ngokufanelekileyo, kwaye eyona nto ipheleleyo. ukugcinwa Amaqela asebenzayo e-amino acid, kwaye abe yi-collagen ye-hydrolyzed ene-molecular weight of 2000-5000 Daltons.

Inkqubo yokuvelisa ifezekisa inqanaba eliphezulu lomsebenzi webhayoloji kunye nokucoceka ngokusebenzisa ukuhluzwa okuphindaphindiweyo kunye nokususwa kwee-ion zokungcola, kunye nenkqubo ye-sterilization yesibini kubandakanya ukushisa okuphezulu kwe-140 ° C ukuqinisekisa ukuba umxholo webhaktheriya ungaphantsi kwe-100 / g (eli nqanaba i-microorganisms iphezulu kakhulu kune-1000 / g yomgangatho we-EU), kwaye i-spray-yomile nge-granulation ekhethekileyo yesibini ukuze yenze i-soluble, i-digestible ngokupheleleyo i-hydrolyzed collagen powder.Inyibilika emanzini abandayo, igaywa lula kwaye ifunxwe.

Izinto eziluncedo kwi-Hydrolyzed Collagen

(1) I-collagen ene-Hydrolyzed inokufunxa kakuhle kwamanzi:

Ukufunxa amanzi kukukwazi ukufunxa okanye ukufunxa amanzi.Emva kwe-collagenase hydrolysis, i-collagen ye-hydrolyzed yenziwa, kwaye inani elikhulu lamaqela e-hydrophilic abonakaliswe, okubangelwa ukwanda okukhulu kwamanzi.

(2) Ukunyibilika kwe-hydrolyzed collagen kulungile:

I-solubility yamanzi yeprotheni ixhomekeke kwinani lamaqela e-ionisable kunye namaqela e-hydrophilic kwi-molecule yayo.I-hydrolysis ye-collagen ibangela ukuqhawuka kwamabhondi e-peptide, okukhokelela kumaqela athile e-polar hydrophilic.

Ukunyuka kwenani (njenge-COOH, -NH2, -OH) kunciphisa i-hydrophobicity yeprotheni, ukwandisa ukuxinwa kwentlawulo, ukwandisa i-hydrophilicity, kunye nokwandisa ukunyibilika kwamanzi.

(3) Umthamo ophezulu wokugcina amanzi kwi-collagen ene-hydrolyzed:

Amandla okugcina amanzi eprotheni achatshazelwa kukugxilwa kweprotheyini, ubunzima bemolekyuli, iintlobo ze-ion, izinto zokusingqongileyo, njl.

Njengoko iqondo le-collagen hydrolysis lisanda, izinga lokugcinwa kwamanzi linyuka ngokuthe ngcembe.

(4) I-Chemotaxis ye-hydrolyzed collagen kwi-fibroblasts:

I-Prolyl-hydroxyproline iya kubonakala egazini le-peripheral emva kokungeniswa komntu kwi-collagen ye-hydrolyzed, kwaye i-prolyl-hydroxyproline inokuvuselela ulusu I-Fibroblasts ikhule, ikhulise inani le-fibroblasts efudukayo eluswini, iphucule ukuguqulwa kweeseli ze-epidermal, isantya sokuhamba kwamanzi ngokusebenzisa umaleko wolusu, uphucula isakhono sokuthambisa ulusu, kwaye uthintele ukwakheka kwemibimbi enzulu.

Ukusetyenziswa kwe-Hydrolyzed Collagen kwi-Cosmetics

I-Collagen i-enzymatic hydrolyzed ukuze yenze i-collagen ye-hydrolyzed, kwaye isakhiwo sayo se-molecular kunye nobunzima be-molecular butshintshwa, okubangelwa utshintsho kwiimpawu zayo zokusebenza ezifana nokufunxa kwamanzi, ukunyibilika, kunye nokugcinwa kwamanzi.

I-chemotaxis ye-hydrolyzed collagen kwi-fibroblasts ikhuthaza ukukhula kwe-fibroblasts eluswini, inyusa kakhulu ingxinano ye-fibroblast, i-collagen fiber diameter kunye noxinaniso, kunye nepesenti ye-dermatan sulfate kwi-decorin, yenza ulusu lomelele ngoomatshini Ukunyuka, ukuphuculwa kweepropathi zoomatshini, ukonyuka kokuthamba kunye nokuthamba. ukuqina, amandla okuqina okuthambisa, kunye nokuphucula imibimbi ecolekileyo nenzulu yolusu.