IHyaluronidase |37326-33-3
Inkcazo yeMveliso:
I-Hyaluronidase yi-enzyme enokuthi i-hydrolyze i-hyaluronic acid (i-hyaluronic acid yinxalenye ye-tissue matrix ene-Diffusion effect yokukhawulela amanzi kunye nezinye izinto ezingaphandle kwe-extracellular).
Inokunciphisa okwethutyana i-viscosity ye-intercellular substance, ikhuthaze i-subcutaneous infusion, i-exudate egcinwe kwindawo okanye igazi ukukhawulezisa ukusabalalisa kunye nokuququzelela ukuxutywa, kwaye i-dispersant ebalulekileyo yeziyobisi.
Isetyenziswe ngokweklinikhi njenge-ejenti yokutyhulwa kweziyobisi ukukhuthaza ukuxutywa kweziyobisi, ukukhuthaza i-edema yendawo okanye i-hematoma dissipation emva kotyando kunye nokwenzakala.
| INTO | SPEC |
| PH Ixabiso | 5.0 - 8.5 |
| Ubungakanani obuyinxenye | 100%Nge-80 Mesh |
| Isivavanyi | 98% |
| Ilahleko ekomisweni | ≦5.0% |
| Umsebenzi | Akukho ngaphantsi kwama-300(400~1000)IU/mg, kwinto eyomileyo |
| Ukuhanjiswa kokukhanya | T550nm>99.0% |
| Ukubalwa kwePleti iyonke | ≤1000cfu/g |
| Iyonke iYeast & Mold | ≤100cfu/g |
| Iimeko zokugcina | 2-8°C |
IiNkcazo zeeMveliso
Ingcaciso yeMveliso:
I-flocculent lyophilized emhlophe okanye ekhanyayo, ayinavumba, inyibilika ngokulula emanzini, ayinyibiliki kwi-ethanol kunye ne-acetone, enexabiso eliphezulu le-pH le-4.5-6.0.
Uzinzo: Imveliso eyomiswe ngumkhenkce ayinakuncipha kakhulu kumandla emva kokugcinwa kwi-4 ℃ unyaka omnye;
Ngaphantsi kwemeko ye-42 ℃, umsebenzi uhlala ungatshintshi emva kokufudumeza imizuzu engama-60;Ukushisa kwi-100 ℃ imizuzu emi-5 ukugcina ama-80% amandla;Izisombululo eziphantsi kwamanzi ezigxininisiweyo zilungele ukungasebenzi, kwaye ukongeza i-NaCl kunokunyusa ukuzinza kwazo;Kulula ukuwohloka xa evezwe kubushushu.
I-inhibitors ibandakanya i-ion zetsimbi enzima (Cu2 +, HR <2 +, Fe<3 + Chemalbook, Mn<2+, Zn<2+), idayi eziphilayo ze-asidi, i-bile salts, i-polyanions, kunye ne-polysaccharides ephezulu ye-molecular weight njenge-Chondroitin sulfate B, iheparin, kunye ne-heparan sulfate.
I-activator yi-polycation.I-coefficient yokuxutywa kwe-1% yesisombululo samanzi kwi-280nm yi-8. I-Hyaluronidase i-hydrolyzes i-N-acetyl kwi-hyaluronic acid-β- Phakathi kwe-D-glucosamine kunye ne-D-glucuronic acid i-β-1,4-bond, ivelisa i-tetrasaccharide i-residues i-monocosaccharide residues. impendulo: acid hyaluronic + H2O oligosaccharides.
Isicelo:
1. Isetyenziselwa uphando lwe-biochemical
2. Ngonyango, isoloko isetyenziselwa ukukhuthaza ukuchithwa kwe-edema yendawo okanye i-hematoma emva kokuhlinzwa kunye nokulimala, ukunciphisa intlungu kwindawo yokujova, kunye nokukhawuleza ukuxutywa kwe-injection subcutaneous kunye ne-Intramuscular injections.
3. Ingasetyenziselwa ukunamathela kwamathumbu emathunjini.
Umqulu: 1g, 5g, 10g, 30g, 50g, 100g, 500g, 1kg, 5kgs, 10kgs,25 kgs/ibhegi okanye njengoko ucela.
Ugcino:Gcina kwindawo engenamoya, kwindawo eyomileyo.
Umgangatho wesiGqeba:Umgangatho wamazwe ngamazwe.