I-Pyridoxal 5′-Phosphate Monohydrate | 41468-25-1
Ingcaciso yeMveliso
I-Pyridoxal 5'-phosphate monohydrate (PLP monohydrate) yindlela esebenzayo ye-vitamin B6, eyaziwa ngokuba yi-pyridoxal phosphate.
Ulwakhiwo lweMichiza: I-Pyridoxal 5'-phosphate iphuma kwipyridoxine (ivithamin B6), equlathe iringi yepyridine edityaniswe nekhabhoni yeswekile ye-five-carbon ribose, kunye neqela le-phosphate elidityaniswe kwi-5' carbon ye-ribose. Ifom ye-monohydrate ibonisa ubukho be-molecule yamanzi enye kwi-molecule ye-PLP.
Indima yebhayoloji: I-PLP luhlobo olusebenzayo lwe-coenzyme ye-vitamin B6 kwaye isebenza njenge-cofactor kwiintlobo ezininzi ze-enzymatic reactions emzimbeni. Idlala indima ebalulekileyo kwi-amino acid metabolism, i-neurotransmitter synthesis, kunye nokuhlanganiswa kwe-heme, i-niacin, kunye ne-nucleic acid.
Iimpendulo ze-Enzymatic: I-PLP isebenza njenge-coenzyme kwiimpendulo ezininzi ze-enzymatic, kubandakanywa:
Iimpendulo ze-Transamination, ezidlulisela amaqela e-amino phakathi kwee-amino acids.
Iimpendulo ze-decarboxylation, ezisusa i-carbon dioxide kwii-amino acids.
Racemization kunye nokuphelisa iimpendulo ezibandakanyekayo kwi-amino acid metabolism.
Imisebenzi yePhysiology
I-Amino Acid Metabolism: I-PLP ibandakanyeka kwi-metabolism ye-amino acids ezifana ne-tryptophan, i-cysteine, kunye ne-serine.
I-Neurotransmitter Synthesis: I-PLP ithatha inxaxheba kwi-synthesis ye-neurotransmitters efana ne-serotonin, i-dopamine, kunye ne-gamma-aminobutyric acid (GABA).
I-Heme Biosynthesis: I-PLP iyadingeka kwi-synthesis ye-heme, inxalenye ebalulekileyo ye-hemoglobin kunye ne-cytochromes.
Ukubaluleka kwezondlo: I-Vitamin B6 sisondlo esibalulekileyo ekufuneka sifunyenwe ekutyeni. I-PLP ifumaneka kwiintlobo ezahlukeneyo zokutya, kubandakanywa inyama, intlanzi, iinkukhu, iinkozo ezipheleleyo, amantongomane kunye nemifuno.
Ukubaluleka kweKlinikhi: Ukunqongophala kwe-Vitamin B6 kunokukhokelela kwiimpawu ze-neurological, i-dermatitis, i-anemia, kunye nokukhubazeka komzimba. Ngokwahlukileyo, ukutya kakhulu kwe-vitamin B6 kunokubangela ubutyhefu be-neurological.
Iphakheji
25KG/BAG okanye njengoko ucela.
Ugcino
Gcina kwindawo engenamoya, kwindawo eyomileyo.
Umgangatho woLawulo
Umgangatho wamazwe ngamazwe.