Magnolia Cortex Extract 2% Honokiol | 35354-74-6

I-Magnolia officinalis extract (igama lesiNgesi: Magnolia officinalis PE ), izithako ezisebenzayo: kunye ne-magnolol, i-magnolol, i-magnolol iyonke i-phenol. Umthombo we-Botanical: Isithako esisebenzayo kumsebenzi we-antibacterial kwi-bark ye-Magnolia officinalis Rehder et Wilson, iyeza lemveli laseTshayina.

Le mveliso i-off-white powder crystal. Inyibilika kwibenzene, ether, chloroform, acetone, insolble in water, lula ukunyibilika kwisisombululo sealkali esixubileyo ukufumana ityuwa yesodium. Iqela le-phenolic hydroxyl kulula ukuba i-oxidized, ngelixa iqela le-alyl lilula ukufumana impendulo yokongeza.

Inefuthe elikhethekileyo, elihlala ixesha elide lokuphumla kwemisipha kunye nefuthe elinamandla le-antibacterial, elinokuthi lithintele ukuhlanganiswa kweplatelet.

Ngokweklinikhi, isetyenziswa kakhulu njengeyeza lokulwa ne-antibacterial kunye ne-antifungal. Le mveliso kufuneka ivalwe kude nokukhanya kwaye igcinwe kwindawo eyomileyo, epholileyo kunye nomoya ococekileyo.

Ukusebenza kunye nendima yeMagnolia Cortex Extract 2% Honokiol: 

Ukuchasana nokudumba

Kwimpendulo yokuvuvukala, i-cell membrane phospholipids ikhulula i-arachidonic acid (AA) phantsi kwesenzo se-phospholipase A2.

Kukho iindlela ezimbini ze-metabolic ze-AA, enye kukuvelisa i-prostaglandins kunye ne-thromboxanes ngesenzo se-cyclooxygenase (COX), kwaye enye kukuvelisa i-prostaglandins kunye ne-thromboxanes ngesenzo se-cyclooxygenase (COX). Isenzo se-lipoxygenase (LO) sivelisa i-leukotrienes (LT).

I-Honokiol kwiindawo eziphezulu zithintele umsebenzi we-COX kwiiseli eziphazamisayo, ngelixa zivimbela indlela ye-LO metabolic. Ngoko ke, i-honokiol yi-inhibitor emibini ye-COX kunye ne-LO.

Umphumo wokuchasana nokudumba kwe-honokiol unokunxulunyaniswa nokuthintela kwayo iindlela ezimbini ze-metabolic ze-AA. Ukongezelela, i-honokiol inokuthintela ukukhululwa kwe-lysosomal enzymes, ukunciphisa ukunyanzeliswa kweendonga ze-capillary malunga nendawo yokuvuvukala, kwaye inqanda ukufuduka kwe-leukocyte kunye nokwanda kwezicubu ze-fibrous.

I-Antioxidant

I-Magnolol kunye ne-Honokiol zineempembelelo ze-radical scavenging zamahhala, ezinokutshabalalisa i-parahydroxyl radicals kunye ne-hydrogen peroxide.

Kwangaxeshanye, inokukhusela umsebenzi we-mitochondrial chain chain enzymes ngokuchasene ne-NADPH-induced peroxidative stress, antagonize hemolysis oxidative yeeseli ezibomvu zegazi, kwaye inhibit lipid peroxidation.

Izifundo ezininzi ze-in vitro kunye ne-vivo ziye zavavanya umsebenzi we-antioxidant we-Magnolia officinalis extract, ephindwe ka-1000 yomelele kune-alpha-tocopherol.