L-Carnitine | 541-15-1
IiNkcazo zeeMveliso
I-L-carnitine, ngamanye amaxesha ibizwa ngokuba yi-carnitine nje, sisondlo esenziwe kwi-amino acids methionine kunye ne-lysine esibindini nasezintso kwaye igcinwe kwingqondo, intliziyo, izicubu zemisipha kunye nesidoda. Uninzi lwabantu luvelisa izixa ezaneleyo zesi sondlo ukuze bahlale besempilweni. Ezinye izifo zonyango, nangona kunjalo, zinokuthintela i-carnitine biosynthesis okanye inqanda ukuhanjiswa kwayo kwiiseli zezicubu, ezifana ne-intermittent claudication, isifo senhliziyo, kunye neengxaki ezithile zofuzo. Amanye amayeza angaphinda achaphazele kakubi i-carnitine metabolism emzimbeni.Umsebenzi oyintloko we-L-carnitine kukuguqula i-lipids, okanye amanqatha, kwi-fuel for energy.
Ngokukodwa, indima yayo kukuhambisa i-acids enamafutha kwi-mitochondria yeeseli ze-eukaryotic ezihlala kwiinwebu ezikhuselayo ezijikeleze iiseli. Apha, i-fatty acids ingena kwi-beta oxidation kwaye iyancipha ukwenza i-acetate. Esi siganeko yinto ekhaba umjikelezo we-Krebs, uchungechunge lweempendulo ze-biological eziyinkimbinkimbi eziyimfuneko ukubonelela amandla kwiseli nganye emzimbeni. Ngelishwa, esi sondlo siyancipha ngaphantsi kwethambo kunye ne-osteocalcin, iprotheni efihliweyo yi-osteoblasts ebandakanyekayo kwi-bone mineralization. Enyanisweni, ezi ntsilelo zezona zinto ziphambili ezibangela ukuba i-osteoporosis kubasetyhini be-postmenopausal. Uphononongo lubonise ukuba le meko ingatshintshwa nge-L-carnitine supplementation, eyandisa amanqanaba akhoyo e-osteocalcin.
Eminye imiba enokuthi i-L-carnitine yonyango ingajongana nayo ibandakanya ukusetyenziswa kwe-glucose ephuculweyo kwi-diabetics, ukunciphisa iimpawu ezinxulumene nesifo esingapheliyo sokukhathala, kunye nokuphucula ukulawulwa kwe-thyroid kubantu abane-hyperthyroidism. Kukho ubungqina obubonisa ukuba ipropionyl-L-carnitine inokunceda ekuphuculeni ukungasebenzi kakuhle kwe-erectile kumadoda, kunye nokuphucula ukusebenza kwe-sidenafil, iyeza elithengiswa phantsi kwe-trademark Viagra. Ukongeza, uphando lubonise ukuba esi sondlo siphucula ukubala kwesidoda kunye nokuhamba.
Inkcazo
IZINTO | Iinkcukacha |
Imbonakalo | Iikristale eziMhlophe okanye umgubo wekristale |
Ukuchongwa | Indlela yeMichiza okanye i-IR okanye i-HPLC |
Imbonakalo yesisombululo | Icacile kwaye ayinaMbala |
Ukujikeleziswa okuthe ngqo | -29°∼-32° |
PH | 5.5-9.5 |
Isiqulatho samanzi =<% | 1 |
Isivavanyi % | 97.0∼103.0 |
Intsalela ekutshisweni =<% | 0.1 |
Intsalela yeEthanol =<% | 0.5 |
Iintsimbi ezinzima =<PPM | 10 |
Arsenic = <PPM | 1 |
Ikloridi =<% | 0.4 |
Inkokeli =< PPM | 3 |
IMercury =<PPM | 0.1 |
I-Cadmium = <PPM | 1 |
Ubalo lwepleyiti lulonke = | 1000cfu/g |
Igwele kunye nokungunda = | 100cfu/g |
E. Coli | Ibi |
Salmonella | Ibi |