Iopamidol|60166-93-0

I-Iopamidol, ekwaziwa ngokuba yi-iodopeptidol, iodopentanol, iopamidol, iopamidol, iodobidol, iopamisone, sisiyobisi esingeyo-ionic enyibilikayo emanzini, elichiza lokuxilongwa kwemifanekiso. Ubume bayo beekhemikhali I-amide compounds ye-triiodoisophthalic acid derivatives ine-toxicity ephantsi kwiindonga zemithambo yegazi kunye nemithambo-luvo, ukunyamezela okulungileyo kwendawo kunye nenkqubo, uxinzelelo oluphantsi lwe-osmotic, i-viscosity ephantsi, ukungafani okuhle, isitofu esizinzile, kunye ne-deiodination encinci kakhulu kwi-vivo. I-Myelography kunye nezigulane ezinomngcipheko ophezulu wokuphendula ngokungafaniyo. Emva kwenaliti ye-intravascular ye-iopamidol, ikhutshwa ikakhulu kwizintso. I-T1/2 iyahluka ngokusebenza kwezintso, ngokuqhelekileyo i-2 kwiiyure ze-4, kwaye ikhutshwe ngokukodwa kwifom yasekuqaleni kunye nomchamo, i-90% ukuya kwi-95% ikhutshwe kwiiyure ezi-7 ukuya kwezi-8, kwaye phantse i-100% ikhutshwe kwiiyure ezingama-20. Kwi-vivo, i-iopamidol ayinayo i-metabolized, ayibopheli kwiiprotheni ze-plasma, kwaye ayiphazamisi i-isoenzymes. Ngenxa yomxholo ophezulu we-iodine, le mveliso inciphisa i-X-rays ukufezekisa injongo yokulinganisa i-imaging, kwaye ifanelekile ukungafani kwe-X-ray ye-injection ye-intravascular. I-Iopamidol isetyenziswa ngokweklinikhi kwii-angiography ezahlukeneyo, ezifana ne-cerebral arteriography. I-cardiovascular angiography ibandakanya i-coronary arteries, i-thoracic kunye ne-abdominal arteries, i-peripheral arteries, i-veins, kunye ne-digital subtraction angiography. Kwaye i-urinary tract, i-joints, i-fistula, intambo yomgogodla, i-tank kunye ne-ventricle, i-arteriography ekhethiweyo ye-visceral. Ukuskena okuphuculweyo kuviwo lweCT.