I-Gotu Kola Extract 40% Asiaticosides | 16830-15-2

Intshayelelo yeGotu Kola isicatshulwa 40% Asiaticosides:

I-Centella asiatica, ingca eyomileyo ye-Centella asiatica, yabhalwa okokuqala kwi-"Shen Nong's Materia Medica" kwaye idweliswe njengebanga eliphakathi.

Ineempembelelo zokucoca ubushushu kunye nokufuma, ukukhupha ityhefu kunye nokunciphisa ukudumba. Ukunyangwa kwamanxeba, izifo zesikhumba, njl.

Izithako eziphambili ezisebenzayo kwi-Centella asiatica extract ezinokuthi zisetyenziswe kwizinto zokuthambisa ziyi-asiatic acid, i-madecassic acid, i-madecassoside kunye ne-madecassoside, i-madecassoside yi-saponin ye-triterpenoid ye-Centella asiatica Yenye yezinto ezisebenzayo ezinomlinganiselo ophezulu, obala malunga ne-30% yeGlycosides iyonke yeCentella asiatica.

Ukusebenza kunye nendima yeGotu Kola isicatshulwa i-40% Asiaticosides: 

I-antibacterial

I-Centella asiatica extract iqulethe i-asiatic acid kunye ne-madecassolic acid, ezi saponins ezisebenzayo ziya kwenza i-cytoplasm kwiiseli zezityalo, lo msebenzi we-antibacterial unokukhusela isityalo ngokwaso ekuhlaselweni ngumbumba kunye negwele, uvavanyo lubonisa ukuba iCentella asiatica.

Isicatshulwa sinempembelelo ethile yokuthintela kwiPseudomonas aeruginosa, iStaphylococcus aureus kunye nePropionibacterium acnes.

Ukuchasana nokudumba

I-Centella asiatica iyonke i-glycosides ineempembelelo ezichasayo ezicacileyo: ukunciphisa imveliso ye-pro-inflammatory mediators (L-1, MMP-1), iphucula kwaye ilungise umsebenzi womqobo wolusu, ngaloo ndlela ikhusela kwaye ilungisa ukungasebenzi kwe-immune yesikhumba.

Ukuphilisa amanxeba kunye namanxeba

I-Madecassoside kunye ne-madecassoside zizinto ezisebenzayo ze-Centella asiatica kunyango lwezilonda zokutshisa.

Bangakwazi ukukhuthaza i-collagen synthesis kunye ne-angiogenesis emzimbeni, ukuvuselela ukukhula kwe-granulation kunye nezinye iindima ezibalulekileyo, ngoko ziluncedo ekuphulukiseni amanxeba.

Kwangaxeshanye, i-asiaticoside inefuthe lokwanda kwi-epidermal keratinocytes kunye neeseli ze-vascular endothelial, kwaye inefuthe elithintelayo kwi-fibroblasts, ngaloo ndlela ikhuthaza ukubunjwa kwezicubu zegranulation kwinqanaba lokuqala lokuphola kwesilonda, kwaye inqanda ukuvela kwesiva kwinqanaba lokugqibela. isiphumo sokuphilisa isilonda.

Ukuchasa ukuguga

I-Centella asiatica extract inokukhuthaza ukuhlanganiswa kwe-collagen I kunye ne-III, kunye nokukhupha i-mucopolysaccharides (njenge-synthesis ye-sodium hyaluronate), ukwandisa ukugcinwa kwamanzi eluswini, kusebenze kwaye kuhlaziywe iiseli zesikhumba, zithobe, ziphucule kwaye ziphucule ulusu. Menyezela.

Kwelinye icala, uvavanyo lolandelelwano lwe-DNA lufumanise ukuba i-Centella asiatica isicatshulwa iphinda isebenze iijene ze-fibroblast, ezinokonyusa amandla eeseli ze-basal zesikhumba, zigcine ukunwebeka kunye nokuqina kolusu, kunye nemibimbi yobuso egudileyo.

I-Antioxidant

I-Asiaticoside, i-madecassoic acid kunye ne-madecassoic acid zonke zinemisebenzi ecacileyo ye-antioxidant.

Iziphumo zovavanyo lwezilwanyana zibonisa ukuba i-madecassoside inokubangela i-superoxide dismutase yendawo, i-glutathione kunye ne-peroxidase kumanxeba kwinqanaba lokuqala lokuphiliswa kwesilonda.

Amanqanaba e-antioxidants afana ne-catalase, i-VitChing, i-VitE yanda kakhulu, kwaye inqanaba le-lipid peroxides kwisilonda lancitshiswa ngamaxesha e-7.

Ukwenza mhlophe

I-Asiaticoside inokuthintela umsebenzi we-tyrosinase ngendlela exhomekeke kwidosi, kwaye i-4μg / ml i-asiaticoside inqanda i-tyrosinase nge-4%.