Cytidine | 65-46-3

I-Cytidine yi-molecule ye-nucleoside eyenziwe yi-nucleobase cytosine edityaniswe ne-sugar ribose. Ngenye yeebhloko zokwakha ze-RNA (i-ribonucleic acid) kwaye idlala indima ebalulekileyo kwimetabolism yeselula kunye ne-nucleic acid synthesis.

Isakhiwo seMichiza: I-Cytidine iqukethe i-pyrimidine nucleobase cytosine efakwe kwi-five-carbon sugar ribose ngokusebenzisa ibhondi ye-β-N1-glycosidic.

Indima ye-Biological: I-Cytidine yinxalenye ebalulekileyo ye-RNA, apho isebenza njengenye yee-nucleosides ezine ezisetyenziselwa ukwakhiwa kwemicu ye-RNA ngexesha lokubhalwa. Ukongeza kwindima yayo kwi-RNA synthesis, i-cytidine iphinda ithathe inxaxheba kwiindlela ezahlukeneyo ze-metabolic, kubandakanywa ne-biosynthesis ye-phospholipids kunye nokulawulwa kwe-gene expression.

I-Metabolism: Ngaphakathi kweeseli, i-cytidine inokuba yi-phosphorylated ukuze yenze i-cytidine monophosphate (CMP), i-cytidine diphosphate (CDP), kunye ne-cytidine triphosphate (CTP), ezingundoqo ezibalulekileyo kwi-nucleic acid biosynthesis kunye nezinye iinkqubo ze-biochemical.

Imithombo yokutya: I-Cytidine ifumaneka ngokwemvelo kwizinto ezininzi zokutya, kuquka inyama, intlanzi, iimveliso zobisi kunye nemifuno. Inokufumaneka kwakhona ngokutya ngendlela ye-cytidine-equkethe i-nucleotides kunye ne-nucleic acids.

Amandla oNyango: I-Cytidine kunye nezinto eziphuma kuyo ziye zaphandwa ngenxa yezicelo zabo zonyango ezinokubakho kwiimeko ezahlukeneyo zonyango, kubandakanywa ukuphazamiseka kwe-neurological, umhlaza, kunye nosulelo lwentsholongwane. Ngokomzekelo, i-cytidine analogs ezifana ne-cytarabine zisetyenziselwa i-chemotherapy ukunyanga iintlobo ezithile ze-leukemia kunye ne-lymphoma.